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It Is Best To Carry On Taking Antidepressants While Breastfeeding, Since ...


It is best to carry on taking antidepressants while breastfeeding, since only minute amounts will be transferred to the baby. Livers and kidneys develop rapidly in babies only a few weeks old, helping to breakdown and filter antidepressants in the blood stream.
Aim
The aim of the current review was to appraise evidence on the safety and effectiveness of antidepressants in the management of PND.

CHAPTER TWO
LITERATURE REVIEW
The evidence/data to be reviewed here is based on a comprehensive search of multiple databases including HIGHWIRE Press, ACADEMIC SEARCH PREMIER (access through EBSCO databases), PsychINFO, INTERNURSE, and the BRITISH MEDICAL JOURNAL database. The Internet was also searched with emphasis on peer-reviewed published journal articles. Key words included: ‘antidepressants', ‘depression', and ‘postnatal depression'. There were no problems of access: all the databases reviewed are available to the general public through university library resources and/or Athens protected resources. These particular databases were chosen because of their emphasis on psychological, biomedical, and practice-based literature, and easier access to full-text files. For example, PsychINFO contains more than 1,500,000 references to journal articles, books, technical reports, and dissertations, published in numerous countries. As a form of psychopathology, PND is comprehensively addressed. INTERNURSE provides access specifically to the nursing literature and incorporates may key journals (e.g. British Journal of Nursing, Nurse Prescribing, Practice Nursing, and the International Journal of Palliative Nursing). HIGHWIRE Press is one of the two largest archives of free full-text science databases available, providing access to thousands of psychobiomedical journal articles and books. ACADEMIC SEARCH PREMIER incorporates over 4000 scholarly journals and 3100 peer review articles. These databases were preferred to others such as SCIENCE DIRECT, have a more general emphasis on scientific (rather than clinical, medical) literature, or not provide sufficient access to full-text articles.
Only studies that satisfied the following criteria were eligible to be reviewed:
Empirical studies using either qualitative or quantitative methods. Thus, this included case studies, questionnaire surveys, retrospective/prospective designs, and randomised controlled trials (RCT).
Review articles and meta-analysis, including cochrane reviews.
Focus on the effects of antidepressants on mother and/or child, and with or without breast-feeding.
Focus on postnatal depression, at any stage (i.e. postpartum ‘blues', depression, and puerperal psychosis [Beckford-Ball, 2000]).
Focus on mothers perceptions of antidepressants as treatment for postnatal depression.

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